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From the global analysis it is apparent that many eukaryotic proteins/enzymes are hormonally regulated by phosphorylation/dephosphorylation mechanisms, and small molecules (primary metabolites) are phosphorylated to keep the phosphorylated compounds trapped inside the cell

Additionally, MK-677 enhances sleep architecture by extending slow-wave sleep phases, which represents the deepest stage of rest

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Yue J, Lpez JM