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Phase 2: Sculpt What Remains (Month 6+) After weight loss, many patients have stubborn fat pockets that diet and medication cannot address

however, selonsertib did not demonstrate either clinically meaningful improvement in MELD or short-term survival in a randomized phase 2 trial (NCT02854631) [57]

Merck: Notably, Merck has no approved obesity drug in 2025

The researchers noted it is crucial in the removal and detoxification of carcinogens thanks to its antioxidant effects (12)

Trimetazidine, a metabolic modulator, has cardiac and extracardiac benefits in idiopathic dilated cardiomyopathy