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2.2.3 Puerarin Puerarin is an isoflavonoid isolated from the root of the plant Pueraia and has been widely used in traditional Chinese herbal medicine for the treatment of various renal diseases, such as renal fibrosis, diabetic kidney disease, kidney stone, acute kidney injury (AKI) and CKD (Xueling et al., 2024

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Nevertheless, fluorescence-based biodistribution analysis cannot fully exclude trace systemic absorption of EGCG, Zn, or their metabolites, and minor systemic contributions cannot be ruled out

When this happens, it allows better absorption and faster action

SE treatment effectively counteracted this pathological shift