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For each outcome, meta-analyses were repeated for subgroups of schools, and the null hypothesis that effect parameter estimates are constant across subgroups (heterogeneity across subgroups test for NI versus Bogot, and ASSIST versus Dead Cool), was tested using methods described in the Cochrane Handbook (Higgins and Thomas, 2022)

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"The FDA won't tolerate a whole generation of young people becoming addicted to nicotine as a tradeoff for enabling adults to have unfettered access to these same products," said Gottlieb