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We conclude that reduced synthesis contributes to glutathione deficiency in patients with type 2 diabetes, and it is more marked in those with diabetic complications

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DHEA protects mitochondria against dual modes of apoptosis and necroptosis in human granulosa HO23 cells

Park et al., 2012

Recombinant mouse HGF (carrier protein-free) was incubated with GSSSG (A) and LASSS (B) at molar ratios ranging from 1:0 to 1:4000 relative to HGF (corresponding to weight ratios of 1:0 to 1:57 and 1:0 to 1:21 with A and B, respectively) just prior to the optimized peroxynitrite-protocol at a molar ratio 1:2000 relative to HGF, pH 7.4 (Figure 1b,c)

thus, RCTs need to assess their diet-induced metabolic outcomes under consideration of sex as well