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Cagrilintide carries the same proline substitutions at positions 25, 28 and 29 that define pramlintide and suppress fibril formation, together with three further changes, Asn14 to Glu, Val17 to Arg and Tyr37 to Pro, plus acylation of the Lys1 side chain with a C20 fatty diacid through a gamma-glutamate linker

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The Journal of nutrition , 134 (3), 489-492

The first Wegovy lawsuits came soon afterwards