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Standing Orders A standing order is a physicians pre-authorisation for specific procedures to be carried out by nursing staff based on defined criteria, without requiring a specific order for each client

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Authoritative Sources These sources help ground the safety discussion in trial data and official study records

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A recent meta-analysis of randomized controlled trials (RCTs), including AMPLITUDE-O, examining six GLP-1 receptor agonists (lixisenatide, liraglutide, subcutaneous semaglutide, exenatide, dulaglutide, and efpeglenatide) reported a 21% reduction in a composite kidney outcome (macroalbuminuria, doubling of serum creatinine or 40% eGFR decline, RRT, or death from kidney disease), corresponding to a number needed to treat of 47 [73]

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These figures describe reported research handling and are provided solely for research-use-only, non-clinical purposes

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