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For example, in a thioacetamide-induced mouse model, semaglutide reduced biochemical and histological markers of liver injury, attenuated -SMA expression, decreased oxidative stress, and downregulated the canonical TGF-/Smad signalling pathway while upregulating SIRT1 and phosphorylated AMPK

All the statistical analyses were performed using R software, version 4.3.2

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This allows your healthcare provider to monitor for any potential issues and provide appropriate guidance tailored to your individual circumstances

Kidney Function Individuals with kidney disease or reduced kidney function should exercise caution when considering long-term Semaglutide use