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It downregulates inflammatory mediators such as IL-6, indirectly modulating hepc activity and restoring iron homeostasis (87, 88)

4 Sources of data and search methodologies Ethnobotanical information about the claimed MPs found in Ethiopia and their extracts, metabolites, and active compounds, as well as preclinical and clinical efficacy studies done anywhere, was searched and downloaded from global databases such as PubMed, Web of Science, Scopus, SciELO, ResearchGate, Google, Google Scholar, ScienceDirect, and AJOL

A total of 11,611 cysteine sites were detected, of which only 1.8% exhibited increased levels of oxidation following GSH depletion

Biomolecules 6, 6

Discussion Different ubiquitin linkages exert specific roles in regulating biological pathways

Abatacept Abatacept, a recombinant fusion protein also known as cytotoxic T-lymphocyte-associated protein Ig (CTLA4Ig), plays a pivotal role in modulating the immune response by disrupting T cell costimulatory signals