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BLACK BOX WARNING: METFORMIN MAY CAUSE LACTIC ACIDOSIS Postmarketing cases of metformin-associated lactic acidosis have resulted in death, hypothermia, hypotension, and resistant bradyarrhythmias

It is estimated that roughly 40 trillion bacterial cells and up to 1,000 different species of bacteria are found in the gut and make up 1-3% of our overall body weight

It achieves this by directly scavenging reactive oxygen species (ROS), such as hydroxyl radicals and superoxide anions, which are unstable molecules that can tear apart cellular membranes and damage DNA

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doi: 10.1038/sj.bjp.0706912 123 BrhlHCihakJPlachJKunz-SchughartLNiedermeierMDenzelAet al

SELENOP: selenium transport and testicular function SELENOP serves as the main protein that moves selenium through the body and helps testicular selenium metabolism