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It has been demonstrated that OS was not present in HTN-I patients, and significantly, it was lower as compared to a healthy control group in an observational study with 355 subjects (Nuez-Sells et al., 2019)

However, as we age or face increased stress, our natural production of glutathione may begin to decline

Trends Cell Biol (2022) 32(9):80014

This tamping down suggests a reduction in the innate immune response, which could leave someone vulnerable to infections after exposure to zearalenone.[ref] Kidney damage: Oral exposure to ochratoxin A from contaminated food is linked to kidney injury

It is important to note that many of the studies that examined the efficacy of lipoic acid in the treatment of diabetic neuropathy have been primarily conducted by one German research group and funded by the manufacturer of lipoic acid in Germany (82)