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Keller-Hamilton, the epidemiologist, acknowledges that nicotine itself is not carcinogenic, and users do find it has some cognitive benefits

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Formaldehyde : Typically used in embalming fluid, formaldehyde could be present in dip tobacco due to the fermentation or chemical reactions it went through during processing

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Carcinogen biomarkers DNA adducts, protein adducts and urinary metabolites provide objective measures of carcinogen uptake and metabolic activation and detoxification in people who use, or are otherwise exposed to, tobacco products