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Alternatively, altered levels of ACs may be a direct consequence of depression or related clinical aspect such as use of antidepressants

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Unlike the reigning blockbuster GLP-1 drugs on the market namely Novo Nordisks Wegovy (semaglutide) and Eli Lillys Zepbound (tirzepatide), the latter of which is a dual agonist of the GLP-1 and GIP receptors Amgens MariTide is an antibody-peptide conjugate that combines a GLP-1 receptor agonist (consisting of two peptides that mimic the GLP-1 hormone) and GIP receptor antagonist (an antibody that blocks the receptor)

is supported by the NIH, National Institute of General Medical Sciences Training Grant T32-GM008203

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