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This treatment is very successful in replenishing tissues, even if deficiency was caused by malabsorption

J Neurosci 31:73927401 Malik AR, Szydlowska K, Nizinska K, Asaro A, van Vliet EA, Popp O, Dittmar G, Fritsche-Guenther R, Kirwan JA, Nykjaer A, Lukasiuk K, Aronica E, Willnow TE (2019) SorCS2 controls functional expression of amino acid transporter EAAT3 and protects neurons from oxidative stress and epilepsy-induced pathology

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AOD-9604 produced modest weight reductions in human trials, with the most notable 12-week Phase 2 study reporting approximately 2.6 kg average fat mass reduction at the 1 mg daily dose compared with 0.8 kg in placebo-treated participants