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Disclosures Jos Luis Grriz has served as consultant to Boehringer Ingelheim, Mundipharma, AstraZeneca, and Novo Nordisk and has received speaker honoraria from Boehringer Ingelheim, Mundipharma, AstraZeneca, Novo Nordisk, Novartis, and Eli Lilly and Company

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Adding phentermine, which can also cause gastrointestinal disturbance and dry mouth, may compound these symptoms and reduce treatment tolerability

Cagrilintide has a plasma half-life of approximately 159 hours (~7 days) thanks to the acylated C20 fatty acid binding to albumin, which enables once-weekly dosing

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