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Non-specific MMP inhibitors are mainly developed as anticancer agents, but they have been reported to cause side effects such as arthritis, so long-term use as a COPD treatment drug may have hidden dangers

Researchers who have mapped its activity describe GHK-Cu as a peptide that switches on a wide set of repair-related genes, which is part of why a supervised copper peptide protocol like GHK-Cu therapy is studied for both skin and scalp health

For example, SASP reduces GSH expression levels at the cellular level, which induces growth arrest in breast cancer cells and increase the efficacy of anticancer drugs, such as doxorubicin (83), similar to preclinical investigations in vitro and in vivo (84)

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Shibani stresses that these problems need both internal (diet & lifestyle) and external (treatments & Glutathione) care

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