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UK guidance (MHRA and NICE) advises checking B12 levels in patients on metformin who develop symptoms of deficiency (anaemia, neuropathy) and considering periodic monitoring in those on long-term therapy
Protect From Light: Store the vial away from direct light to preserve its potency and effectiveness over time
The net result in animal models is a reduction in adipocyte volume, not adipocyte number
Stern AF
Its sometimes used alongside treatment for depression and anxiety
For observational studies reporting serum vitamin B12 levels, the certainty of evidence was upgraded from low to moderate due to the large and consistent magnitude of effect across studies, despite heterogeneity
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