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Previous reports have shown that miR-483-3p functions as an oncogene by modulating multiple target genes in various human cancers 45 .In the present study, we reveal that miR-483-3p functions as a critical regulator of human NK cell cytotoxicity by directly targeting IGF-1

Moreover, OPi, a novel OXPHOS complex I inhibitor, showed antitumor activity in MAPKi-resistant BRAF-mutant melanoma by promoting glycolytic metabolism and suppressing the TCA cycle through the LKB1-AMPK axis [55]

Increased lipid peroxidation has also been observed concurrent with an increased GPx activity

PMC 3717858

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