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Every neuroprotective application discussed here is investigational or off-label

Unlike nitric oxide-based therapies such as phosphodiesterase type 5 inhibitors, which enhance blood flow through vasodilation, PT-141 stimulates sexual arousal through activation of melanocortin receptors in the brain and spinal cord

pH 3-9

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In our prior study with this TTS model of NIT, we found that acoustic trauma did not result in significant hair cell losseither IHCs or OHCsat any tonotopic frequency position 35