flow trial semaglutide kidney outcomes 2024 nejm hazard ratio FLOWing with the SemagluTIDE — NephJC flow trial semaglutide kidney outcomes

6,10 At baseline, 97% were treated with one or more glucose-lowering medications: metformin (76%), insulin (51%), SGLT-2 inhibitor (27%), sulfonylurea (29%), and DPP-4 inhibitors (23%)

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Endoplasmic reticulum An organelle of eukaryotic cells that is involved in protein synthesis and sorting, and lipid synthesis and metabolism, as well as detoxification