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1 are reversible, class I glutaredoxins can also catalyze the GSSR- or GSSG-dependent glutathionylation of thiols or the formation of (protein) disulfides 3,5,35,61

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This does not diminish the therapeutic value of GLP-1 medications but instead underscores the importance of viewing weight loss through a broader physiological lens that accounts for body composition and long-term cardiometabolic health

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But long-term loss might mean a serious problem, like nerve damage or a neurological disorder