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potentially fatal disturbances of cardiac conduction (widening of QRS), arrhythmias & seizures due to Na channel block (cardiac & CNS) Pharmacokinetics: PO, metabolized in the liver (P450 - 2D6)

This review summarises key contraindications, clinical situations requiring caution, relevant drug interactions, and commonly reported adverse effects associated with KD

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This is one reason medication history matters when unexplained fatigue, muscle weakness, or metabolic abnormalities are being assessed