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An important point patients should understand from the outset: stopping semaglutide abruptly after reaching a target weight often leads to partial weight regain

Written by: Morgan Pennington , 01 Jul 2026 10 min read Reviewed and fact-checked: Niya Mansuri , Prescribing Pharmacist, GPhC No

InjectCo sources from licensed 503B pharmacies and requires a full provider evaluation before prescribing

Because rapid weight loss on GLP-1 agonists includes lean-mass loss, the documented supportive measures are: Adequate dietary protein to help preserve muscle during a caloric deficit

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This effect may be more noticeable during the initial weeks of treatment with GLP-1 receptor agonists