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51, 77 The role of these ions in the regulation of the normal intestinal physiology and pathobiology including mucosal inflammation is well recognized

This could be explained by patients requiring more comprehensive treatment as their disease progresses, therefore moving from a basal to a basal-bolus regimen

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Side effects and safety GHK-CU has an excellent safety profile in research contexts

The closest comparison is with AHK-Cu (Ala-His-Lys with copper), a related copper-binding tripeptide that shares the histidine-anchored coordination chemistry but has alanine rather than glycine at position 1

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