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doi:10.3390/ijms231710136 [Made by author on BioRender] These pathologies, on top of being associated with a degradation of how the Blood-Brain Barrier work, all involve altered processes in the brain implied in the development of the disease

These studies demonstrate inconsistent findings and this inconsistency probably represents the heterogeneity of older people in terms of co-morbidities, liver volume, organ dysfunction and concurrent medications

The management of B12 deficiency is straightforward

IV injections are normally only given in clinics and hospitals

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It is critical to reiterate that long-term human safety data is non-existent