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Sources All clinical data, approval dates, and regulatory information on this page have been verified against primary sources: Sources Knop FK, et al

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Among these, compounds 53 (IC 50 = 4 nM) and 54 (IC 50 = 10 nM) exhibited high DPP-4 inhibitory activities, good efficacy, and selectivity in an oral glucose tolerance test in ICR mice (Figure 7)

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