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TM6 undergoes the characteristic outward rotation that opens the G protein-binding cavity, TM5 repositions to form the lateral wall of this cavity, and the intracellular ends of TM3 and TM7 reorganize to complete the G protein docking surface

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The changes in gene transcription led to changes in the synthesis of proteins that affect various physiological processes, including metabolism, development, and growth

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Nihon Kyobu Shikkan Gakkai zasshi (1992) 30:427