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Immediate medical attention (emergency department or urgent care) is warranted for: Signs of anaphylaxis or severe allergic reaction, including difficulty breathing, throat tightness, rapid pulse, dizziness, or widespread urticaria (call 911) Severe swelling extending beyond the injection site or involving the face, lips, or tongue Signs of significant infection, including fever above 100.4F (38C), purulent drainage, or rapidly spreading erythema with warmth Severe pain disproportionate to visible findings Skin necrosis, blistering, or ulceration at the injection site Scheduled healthcare provider evaluation is appropriate for: Persistent injection site reactions lasting more than 5 to 7 days despite conservative management Recurrent moderate to severe reactions with each injection, suggesting possible hypersensitivity Development of indurated nodules or lipohypertrophy at injection sites Uncertainty about whether symptoms represent normal reactions or require intervention Clinical assessment of concerning injection site reactions typically includes examination of the affected area, review of injection technique, and evaluation for signs of infection or hypersensitivity

Variable surgical options are available, but the two most common are gastric banding (reducing the volume of the stomach to create early satiety) and gastric bypass (reducing the surface area of the bowel to reduce absorption)

Semaglutide Current options: Compounded Sublingual Semaglutide No longer available: Compounded Semaglutide/Tirzepatide for injection Trade Name Availability: (available by special order only, prepayment is required): Wegovy, Ozempic, Rybelsus, Mounjaro, Zepbound Compounded Sublingual Semaglutide Instructions prior to use: Perform normal oral hygiene routine

It's important to note that semaglutide also has a secondary expiration date which kicks in 28 or 56 days after you've removed Wegovy or Ozempic from the fridge

Some evidence suggests that GLP-1 medications might lead to disordered eating patterns or excessive dietary restrictions in certain patients

Its a real problem, and its one I see every week