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The PI3K/Akt signaling pathway has been thoroughly studied and plays a vital role in cell proliferation and survival

HBcAg and B cell epitopes from the preS1 region integrate to induce HBsAg and HBcAg-specific immunity in HBV transgenic mice, activating endogenous dendritic cells without inducing liver damage

Intervention strategies for IR, including pharmacological and non-pharmacological approaches, have shown potential in improving IR and reducing metabolic disorders

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After adding CHX for 3 hours, the ER form was largely reduced while the lysosome form continued to increase (Figure 3, D and E), suggesting that the newly synthesized cystinosin-GFP was trafficked from ER to the lysosome