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New England Journal of Medicine, September 2025

It is important to remember that it should not be used as a substitute for lifestyle changes but rather as an aid to those efforts

In parallel, limited awareness and variable training among primary care providers contribute to under recognition of symptom patterns suggestive of endometriosis

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Other symptoms found in patients with -glutamylcysteine synthetase deficiency are transient jaundice, reticulocytosis, and hepatosplenomegaly

This can mechanically irritate the diaphragm via vagus nerve pathways, which is a known trigger for the hiccup reflex