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Dwivedi AN, Jain S, Dixit R

4.3 Application of gut microbiota in the treatment of UC 4.3.1 Microecological preparation Microecologics include probiotics, prebiotics, and synbiotics

For instance, experiments involving the co-incubation of Caco2-cells with Enterococcus faecalis or Mitsuokella multiacidus bacterial supernatants have shown a significant decrease in GLP-1 mRNA abundance 73

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While this large retrospective study cannot fully prove causality, it provides robust real-world evidence that supports the safety of these medications