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"People don't always appreciate this," says Rubino

Last reviewed: June 22, 2026 Last updated: June 22, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

While neither liraglutide nor semaglutide is FDA-approved for cardiovascular protection, research suggests both may help lower the risk of major heart-related events like heart attack, stroke, or cardiovascular death in people with type 2 diabetes

Reduced appetite (your brain thinks youve eaten enough)

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A combination of strength training, cardiovascular exercise, and mobility work often works well for many individuals