Succinylcholine is a depolarizing neuromuscular blocker that produces a Phase I block via persistent activation of post-synaptic nicotinic receptors, causing depolarization, transient fasciculations, sodium channel inactivation, and flaccid paralysis without fade
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For example, glutamate is the precursor compound for the production of the inhibitory neurotransmitter GABA (110)
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The same conjugation process clears cortisol metabolites, xenoestrogens from plastics and pesticides, and other endocrine-disrupting chemicals that interfere with hormone signalling
