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What reaches circulation is highly variable

Non-surgical treatments have less risk and recovery, but they offer more modest results

We emulated and benchmarked against two cardiovascular outcome trials (reference trials), SUSTAIN-6 (semaglutide versus placebo) and SURPASS-CVOT (tirzepatide versus dulaglutide) in a pair of cohort studies

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Mandatory disposal situations include: Expiry date reached never use medication beyond the printed expiry date, even if unopened and continuously refrigerated