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The secondary objectives were the evaluation of episodes intensity and long-term efficacy for patients treated more than one year

Additionally, the use of Fer-1 or deferoxamine (DFO) has been shown to activate healthy autophagy flux in hyperosmolarity-induced CECs (125)

In addition, inhibiting the expression of SLC7A11 gene will affect the synthesis of glutathione, thereby causing the apoptosis of IDH1 mutant glioma cells

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Conditional knock-out of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation

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