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DNA adduct formation from metabolic 5-hydroxylation of the tobacco-specific carcinogen N -nitrosonornicotine in human enzyme systems and in rats

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However, some tobacco manufacturers in India voluntarily adopt international standards such as 10 mg tar/1 mg nicotine/10 mg carbon monoxide (CO) per cigarette, following the European Union Directive 2001/37/EC 10

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"The sponsors argued that even look-alikes glamorize smoking and encourage children to develop a real tobacco habit -- though there's scant evidence to support that linkage," the op-ed said