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In a 10-2 vote Thursday, the Oncologic Drugs Advisory Committee determined that progression-free survival (PFS) data from the Phase III confirmatory CodeBreaK 200 study could not be reliably interpreted

Results: Replacement of the C-terminal tail had only limited effects on G protein and arrestin recruitment to either receptor

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Lower doses produced moderate weight loss Higher doses produced substantially greater reductions Weight loss increased progressively over time A plateau had not clearly been reached at week 48 This suggests potential for continued weight reduction beyond one year, though long-term data remains under investigation

Are you taking a GLP-1 like Wegovy, Saxenda, Ozempic, or Mounjaro and wondering what you should eat for optimal results