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Transitory reason: Increased competition in the premium snus segment in Swedish market SWMA has lost share in premium segment driven by cannibalization of Premium 1 segment (cans priced at SEK 45+, 55% margins) by Premium 2 (36-40 SEK per can, 49% margins) and shares losses within Premium 2 vs BATs Lundgrens

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KruskalWallis tests were used to compare intergroup differences in the expression of the proinflammatory cytokines (IL-1, IL-6, and TNF-), and MannWhitney U tests were used to test for differences between two groups