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Studies have shown that administration of nicotine in rats causes an increase in Basal layer collagen fibers, destruction of Sertoli cell intercellular connections, chromosomal abnormalities, degenerative germ cells, excessive accumulation of fat droplets in the sperm cytoplasm, and morphological abnormalities in the sperm [37]

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As at Los Alamos, he made a point of promoting interdisciplinary work and emphasised in his speeches the belief that science needed the humanities in order to better understand its own implications, write Bird and Sherwin

Le Houezec J (2003) Role of nicotine pharmacokinetics in nicotine addiction and nicotine replacement therapy: a review