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Clinical research has documented significant weight loss outcomes in controlled trial settings using FDA-approved versions of these medications

Front Pharmacol 11:600255 Zhao M, Ma J, Li M, Zhang Y, Jiang B, Zhao X et al (2021) Cytochrome P450 enzymes and drug metabolism in humans

The reality is that access is opening in stages, not all at once

Insufficient time for the medication to work: While some people may notice changes in the first few weeks, it often takes longer for the full effects to become evident

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