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up to 12 weeks) * The maximum daily dose is 150 mg in older frail patients, those with risk factors for seizures, or in patients with renal/hepatic dysfunction

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For the other cancers, the rates in non-smokers are not known, and thus the usual formula for calculating the population attributable fraction (PAF) is used: where P e is the prevalence of exposure and r is the relative risk in smokers

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ACG Clinical guideline: management of Crohns disease in adults