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Similar content being viewed by others Introduction As temperatures fall below the thermal neutral zone, body temperature is initially maintained by shivering thermogenesis via skeletal muscle and chronically by non-shivering thermogenesis in brown adipose tissue (BAT) 1,2,3

CRHR1 antagonist alleviated depression-like behavior by downregulating p62 in a rat model of post-stroke depression

Common triggers are cardiac disorders, endocrine and metabolic disorders, medication or illicit drug use, or psychosomatic disorders

However, researchers suggested that this difference could be explained by 50% of the patients discontinuing their treatment during the first year, and 80% taking lower dosages

Weissman PN, Carr MC, Ye J, et al