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162 Consequently, targeting the glutamine metabolism pathway, which is essential for cancer cells but dispensable for normal cells, may lead to novel therapeutic approaches to treat refractory tumors

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212,213 Stimulating P2X 7 R in neocortical nerve terminals can block the reuptake of GABA and glutamate by the presynaptic membrane and promote the release of these two neurotransmitters in the cerebral cortex of rats and humans, 214,215 and activation of P2X 7 R reduces the expression of GLAST

Apply a moderate amount on the entire body 2