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IARC Monographs on the Evaluation of Carcinogens Risks to Humans: Tobacco Smoke and Involuntary Smoking

Results Cigarette smoke persistently activated Nrf2 target genes essential for maintenance of the cellular reductive state and survival under conditions of increased oxidative stress in HNSCC regardless of human papillomavirus (HPV) association

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doi:10.1093/ajcn/87.4.801

Toxicol Sci 167:408418 Chen L, Wang H (2019b) eIF4E is a critical regulator of human papillomavirus (HPV)-immortalized cervical epithelial (H8) cell growth induced by nicotine

Key Points Tobacco products cause a variety of cancers, including those of the lung, oral cavity, nasal cavity, larynx, oropharynx, hypopharynx, oesophagus, stomach, liver, pancreas, bladder, ureter, kidney and cervix, and myeloid leukaemia