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We used an adaptive design, which means that part-way through data collection, an interim analysis was conducted to assess how many more participants would need to be recruited for the study to have enough statistical power to detect an effect of pack size

These special devices can help remove smoke and contaminants

The silicone construction can withstand higher temps than a cigarette could ever reach, so let it burn as long as you can handle and know the ring will stay perfectly intact

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The next section will review some of the current arguments and evidence in e-cigarette debates, including the toxicology of e-cigarettes and the arguments about the use of e-cigarettes as a harm reduction tool, which have been used as evidence for pursuing a particular regulatory approach