While acute nicotine exposure elevates blood pressure through multiple mechanisms including sympathetic activation and catecholamine release [7, 8], numerous cross-sectional epidemiological studies have reported that current smokers have similar or even lower blood pressure levels compared with non-smokers [4, 9,10,11,12]
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( 5 ) There, it binds to nicotinic acetylcholine receptors, triggering the release of several neurotransmitters, including dopamine (feelings of reward and pleasure), norepinephrine (focus and alertness), acetylcholine (attention and memory), serotonin (mood and sleep), and beta-endorphone (pain reduction and mood elevation)
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