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In this respect, mtDNA polymorphisms considered to represent normal genetic variation, have been linked with different bioenergetic capacities that may provide an adaptive advantage or altered disease susceptibility 8890

Forray, "so we know that exposure to smoking and other substances at any time during this period can alter susceptibility to substances." Other factors that can make certain people more prone to tobacco addiction include genetics, mental health, drug abuse, and being around family and friends who use tobacco