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Current evidence suggests that if back pain occurs during treatment, it is more likely coincidental or related to indirect factors rather than a direct pharmacologic effect of the medication

Staying hydrated prevents electrolyte depletion, and eating smaller, more frequent meals reduces the digestive load on a stomach that already empties slowly

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In the United States, where Wegovy and Zepbound carry list prices exceeding $1,000 per month, approximately one in eight adults report currently taking a GLP-1 drugbut this represents a small fraction of the more than 40% of American adults classified as obese [52]

Annals of the New York Academy of Sciences, 1040(1), 3947