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The STX Entertainment picture, directed by Peter Segal, marks a return to romantic comedies for Lopez, 49, who established herself as one of the most dependable actresses of the genre after starring in such films as The Wedding Planner and Maid in Manhattan nearly two decades ago

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Cigarette smoke-induced necroptosis and DAMP release trigger neutrophilic airway inflammation in mice

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Tenhunen R, Marver HS, Schmid R (1968) The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase