no LD50 established even at very high doses in rodents No Hormonal Effects: Does not affect testosterone, estrogen, growth hormone, or other hormonal axes Gastric Origin: Derived from a naturally occurring human gastric protein, suggesting good biological compatibility Stability: Unusually stable in gastric acid, supporting oral administration potential Reported Effects: Anecdotal reports of fatigue, nausea in some research subjects TB-500 Safety Profile: (PMID: 20536472) Note: Published safety data is primarily available for Thymosin Beta-4
Legal Status Both 5-Amino-1MQ and AOD-9604 are not approved by the U.S
High-purity compounds designed for laboratory research
A complicating factor in clinical trials has been the significant inter-individual variability in susceptibility to APAP toxicity 14
Administration Differences TB-500 can be injected anywhere subcutaneously because it distributes systemically regardless of injection location
By exploiting docking simulations, Tondo et al
